When Sherlock’s brother Mycroft makes a surprise return to New York, his motivations cause discord between Sherlock and Joan. Meanwhile, a missing person case takes Sherlock and Joan inside the…

The interns finally take their first year medical exams, the biggest test of their careers, and one of them is ill-prepared. Callie grows more suspicious of George and Izzie. The…

Recent events strain Burke and Cristina’s relationship. Mark and Derek must work together when two close-knit brothers seek medical help. One of Meredith’s half sisters is admitted to the hospital.

Meredith and Izzie take up knitting. Derek operates on Andrew, a spelling bee champ with a serious head injury. Bailey gets in on Andrew’s surgery because she’s worried that her…

When a Jeffersonian coworker dies of heart failure, the entire team goes to the wake where, upon viewing the body, Brennan realizes the death was no accident.