Caught in a dangerous situation, Sam and Dean only have each other to rely on. Meanwhile, the fight between the American Hunters and the British Hunters comes to a head.

Looking to get Dean out of the bunker, Sam finds a case for him and Dean to investigate – people are disappearing into thin air with only their clothes left…

Ambushed by angry hunters, Sam and Dean are shot and killed and sent to Heaven. Castiel warns Dean that Zachariah is looking for them in Heaven so they need to…