Meredith works on her relationship with Susan and Thatcher. Cristina has to deal with her mother and Burke’s. Alex continues to tend to Jane Doe/Ava. Meredith and Derek’s relationship has…

Sookie and Sam investigate her most recent vision; Jason helps clean up Amy’s mess; Tara becomes angry with Lettie Mae; Lafayette visits a senator.

After a skull smashes into the windshield of a teenager’s car, the investigation reveals the skull has been gnawed on by human teeth, which implies cannibalism and marks the beginning…