One of Scully’s friends from the FBI academy, now working in the Violent Crimes Unit, asks her to assist him on a homicide investigation involving no clear point of entry….

Clark is drawn to the state penitentery by one of the kryptonian crystals, which Lionel is using to switch bodies with Lex. Clark intervenes and Lionel enters his body instead….

Sam and Dean discover a doctor who, back in 1816, became obsessed with finding the secret of eternal life by taking people’s vital organs. Meanwhile, Bobby finds Bela and Dean…

To obtain a mystic gun capable of destroying the demon that killed their mother, Sam and Dean must team up with their father John and face off against vampires.